incidence and clinical outcome of patients with hypertensive acute ischemic stroke: an update from tertiary care center of central india
نویسندگان
چکیده
introduction: we evaluated the incidence and clinical outcome of patients with hypertensive acute ischemic stroke (ais) admitted to a tertiary care center in central india. in addition, we examined the status of stroke biomarkers namely neuron-specific enolase (nse), glial specific protein (s-100ββ), and inter-α-trypsin inhibitor heavy chain 4(itih4) in the serum of patients suffering from ais with hypertension (htn) and without htn. methods: a total of 104 patients with ais were enrolled for the study. clinical outcome and stroke biomarker levels were evaluated in them at the time of hospital discharge and then followed at 12 months and 18 months after hospital discharge. results: htn is a major risk factor associated with 67%(70.104) of patients with ais. multivariate analysis suggests higher odds of 4.088(95%cl, 0.721–23.179) and 2.437(95%cl, 0.721–23.179) for 12 and 18 months outcome in patients with ais and htn, respectively. serum nse and s-100ββ decreased at the time of discharge as compared to admission level in improved patients suffering from ais with or without htn, whereas levels of itih4 peptides 2 and 7 increased at the time of discharge (compared to its admission level) only in improved patients with ais regardless of htn or non-htn condition. conclusion: htn is one of the major risk factors associated with higher risk of ais as well as long-term unfavourable outcome after ais in central india region. nse, s-100ββ, and itih4 were found to be independent predictors of outcome in patients with ais irrespective of htn and non-htn condition.
منابع مشابه
Incidence and Clinical Outcome of Patients with Hypertensive Acute Ischemic Stroke: An Update from Tertiary Care Center of Central India
Introduction: We evaluated the incidence and clinical outcome of patients with hypertensive acute ischemic stroke (AIS) admitted to a tertiary care center in Central India. In addition, we examined the status of stroke biomarkers namely neuron-specific enolase (NSE), glial specific protein (S-100ββ), and inter-α-trypsin inhibitor heavy chain 4(ITIH4) in the serum of patients suf...
متن کاملIncidence and Clinical Outcome of Patients with Hypertensive Acute Ischemic Stroke: An Update from Tertiary Care Center of Central India
INTRODUCTION We evaluated the incidence and clinical outcome of patients with hypertensive acute ischemic stroke (AIS) admitted to a tertiary care center in Central India. In addition, we examined the status of stroke biomarkers namely neuron-specific enolase (NSE), glial specific protein (S-100ββ), and inter-α-trypsin inhibitor heavy chain 4(ITIH4) in the serum of patients suffering from AIS w...
متن کاملthe role of russia in transmission of energy from central asia and caucuses to european union
پس ازفروپاشی شوروی،رشد منابع نفت و گاز، آسیای میانه و قفقاز را در یک بازی ژئوپلتیکی انرژی قرار داده است. با در نظر گرفتن این منابع هیدروکربنی، این منطقه به یک میدانجنگ و رقابت تجاری برای بازی های ژئوپلتیکی قدرت های بزرگ جهانی تبدیل شده است. روسیه منطقه را به عنوان حیات خلوت خود تلقی نموده و علاقمند به حفظ حضورش می باشد تا همانند گذشته گاز طبیعی را به وسیله خط لوله مرکزی دریافت و به عنوان یک واس...
15 صفحه اولClinical profile and management of HbE-β thalassemia in children: Experience from a tertiary care center in North India
Background: Eβ Thalassemia is characterized by clinical heterogeneity ranging from Non-Transfusion Dependent Thalassemia (NTDT) to Transfusion Dependent Thalassemia (TDT) state, causing management challenges for the clinicians, especially in the pediatric population. Therefore, this study was conducted to give an overview of the clinical profile and management in a tertiary care center. Materi...
متن کاملOutcome of patients with stroke admitted in stroke care unit and Neurologic
Introduction: Admission of patients with severe National Institutes of health stroke scale (NIHSS Score>16) or moderate (NIHSS 8 through 16) acute stroks is different. Taking care of stroke patients admitted in stroke unit care (SCU) is costly. In comparison with admission in general neurology ward, we assessed the outcome of such patients based on stroke care unit (SCU) versus general neurol...
متن کاملThe Outcome of Treatment With Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke
Background: Thrombolytic therapy is the recommended treatment of acute ischemic stroke. It is crucial to evaluate the treatment results with recombinant Tissue Plasminogen Activator (r-TPA) in patients with acute stroke. Objectives: This study aimed to evaluate treatment outcomes with r-TPA in patients with acute stroke in a referral stroke center in Iran. Materials & Methods: In this retrosp...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
basic and clinical neuroscienceجلد ۷، شماره ۴، صفحات ۳۵۱-۳۶۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023